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KMID : 1007520090180010197
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Food Science and Biotechnology
2009 Volume.18 No. 1 p.197 ~ p.201
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Less Weight Gain in Obese Rats by Feeding Biocellulose
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Han Dae-Seok
Song Tae-Cheol
Kim Dong-Woo
Lee Chang-Ho
Kim Young-Eon
Kim In-Ho
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Abstract
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This study evaluated the effect of biocellulose and the diet formulation on reducing body weight gain of obese ratsinduced by high-fat diet for 10 weeks. Thirty male Sprague-Dawley rats were randomly assigned to high-fat diet group (OB-CON), high-fat diet group containing 5% biocellulose (OB-BIO), and high-fat diet group containing 5% dietary formulation(OB-DF). After feeding each diet for additional 10 weeks, body weight gains of OB-BIO and OB-DF groups were lower by3.3 and 4.8%, respectively as compared with that of OB-CON group. Although not significant, measured values of theperirenal and visceral fat pads of OB-BIO and OB-DF groups were lower than those of the OB-CON group. The weight ofinterscapular brown adipose tissue did not show significant difference in all groups. The size of adipocyte in rats was lower inboth OB-BIO and OB-DF groups. Thus, biocelluose and the diet formulation showed the anti-obesity effect.
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KEYWORD
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biocellulose, obesity, high-fat diet, body weight, animal experiment
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